Bone/Intraosseous
Injections
INTRA-OSSEOUS OR (IO) INJECTIONS INVOLVE INJECTING PLATELETS RICH IN GROWTH FACTORS OR BONE MARROW CONCENTRATE INTO A BONE TO TREAT SEVERE FORMS OF OSTEOARTHRITIS OR SUBCHONDRAL BONE OEDEMA.
The most advanced, minimally invasive treatment at OrthoRegen® is Intra-osseous injections. This treatment is reserved for patients with severe osteoarthritis and MRI findings of subchondral oedema. It is also a treatment used for patients with Osteochondral Defects or OCD lesions. Subchondral oedema is a significant pain generator in severe osteoarthritis. It is indicative of small cracks or micro-fractures within the bone and is a sign that the bone beneath the cartilage is weak. Subchondral oedema shown on MRI correlates with more pain than cartilage loss or the presence of a joint effusion. This finding is also a sign that the osteoarthritis is actively progressing.
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We use autologous high dose Platelet Rich Plasma (SC-PRP) with our Concentrated Growth Factors (C-GF), or Bone Marrow Concentrate (BMAC) to inject precisely in the subchondral bone where the damage is taking place.
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Dr Paul Schiavo was among the first in Australia to use intraosseous injections for the management of severe osteoarthritis. He has had the pleasure and honour of meeting the undisputed father of intra-osseous injections, Dr Phillipe Hernigou (France) at international conferences and been honoured to receive advanced training in this technique by world leaders in the USA.
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DOES THE PROCEDURE HURT?
Intra-ossoues injections are performed under local anaesthetic and Nitric Oxide in the OrthoRegen® treatment rooms. Most patients are surprised at how little the procedure hurts. On occasion, it can be performed under twilight sedation in an outpatient surgical centre.
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HOW IS THE RECOVERY?
For most patients, 48-72 hours of increased discomfort can be expected. It is common to actually experience some relief in pain from your condition as the treatment can reduce the pressure inside the bone providing temporary relief. Healing of the subchondral oedema will take weeks to months following the treatment.
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WHAT PATIENTS ARE CANDIDATES FOR IO INJECTIONS?
Patients suffering from severe osteoarthritis with or without subchondral oedema lesions on their MRI are candidates for this procedure. Patients have usually failed conservative measures and are interested in avoiding surgery or are not surgical candidates.
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RESEARCH
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Current Concepts in Intraosseous Platelet-Rich Plasma Injections for Knee Osteoarthritis
Diego Delgadoa, Ane Garatea, Hunter Vincent, Ane Miren Bilbao, Rikin Patel, Nicolás Fiz, SteveSampson, Mikel Sánchez
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Mikel Sanchez et al
Intraosseous Infiltration of Platelet Rich Plasma for Severe Hip Osteoarthritis
Nicolas Fiz et al
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Phillipe Hernigou et al
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